- The role of lipids in the pathophysiology of coronavirus infections
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Milad Zandi, Parastoo Hosseini, Saber Soltani, Azadeh Rasooli, Mona Moghadami, Sepideh Nasimzadeh, Farzane Behnezhad
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Osong Public Health Res Perspect. 2021;12(5):278-285. Published online October 15, 2021
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DOI: https://doi.org/10.24171/j.phrp.2021.0153
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 - Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal environment for viral replication. Therefore, lipids can be considered as potential targets for the development of antiviral agents. This review provides an overview of the roles of cellular lipids in different stages of the life cycle of coronaviruses.
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Citations
Citations to this article as recorded by  - PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication
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Journal of Virology.2022;[Epub] CrossRef
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